Scorpion venom may help treat cancer
Researchers discover that chlorotoxin, a chemical found in scorpion venom, can distinguish cancer from healthy tissue, when applied to tumours.Updated: Jul 17, 2007 14:59 IST
Scientists in the US have claimed that scorpion venom may help in the treatment of a wide range of cancers.
Scorpions occur naturally in parts of Africa, America, India and the Caribbean. The majority of scorpions are harmless to human beings although the sting is extremely painful and requires treatment.
Researchers have found that when applied to tumours, the chemical chlorotoxin found in scorpion venom can distinguish cancer from healthy tissue, even when it affects only a few hundred cells and could improve the treatment of a wide range of cancers, reported the online edition of the Daily Mail.
Scientists believe it will help guide surgeons and result in more successful treatment. "By allowing surgeons to see cancer that would be undetectable by other means, we can give our patients better outcomes," said James Olson, a doctor who led the US research team.
By joining the chemical chlorotoxin to a fluorescent marker, Olson and his team created a molecular beacon that lights up tumours. Painting a suspect area with the compound makes it easier for surgeons to remove every bit of cancer without damaging the surrounding healthy tissue.
This is especially important in the brain, where 80 per cent of recurring malignant tumours appear at the edges of the surgical site. The paint marks out tumours with at least 500 times more sensitivity than a magnetic resonance imaging scan, the researchers found.
The scientists said that in tests on mice, it highlighted brain tumours as small as one millimetre in diameter. They are now preparing for human clinical trials. The researchers said the technique could be used in operating theatres in the US in as little as 18 months.