Juan Martin Del Potro sets up Rafael Nadal clash at Wimbledon

Juan Martin Del Potro set up a quarter-final clash with second-seed Rafael Nadal after getting the better of Giles Simon 7-6 (7/1), 7-6 (7/5), 5-7, 7-6 (7/5).

Juan Martin del Potro set up a Wimbledon quarter-final clash against Rafael Nadal when he downed Gilles Simon of France 7-6 (7/1), 7-6 (7/5), 5-7, 7-6 (7/5) on Tuesday.

Argentina's Juan Martin Del Potro celebrates winning his the fourth round Wimbledon match against France's Gilles Simon. (REUTERS)

In a match suspended from Monday night due to darkness with the Argentine star two sets to one ahead, Del Potro sealed victory on a fifth match point after almost four and a half hours of action on Court Two.

On Wednesday, the 29-year-old will be playing in his first Wimbledon quarter-final since 2013, when he went on to lose to Novak Djokovic in an epic semi-final.

Del Potro trails world number one Nadal 10-5 in career meetings and lost to the Spaniard in straight sets in the semifinal of the French Open 2018.