The 34-year-old Orange is the New Black actress said that rumours about her dating Cruise are untrue and she finds them funny, reported Contactmusic.
"I'm flattered because I think he's hot, so I'm like, 'Oh, that's nice,' and apparently he's very gentlemanly with me. Apparently we get along great and he knows that I have a favourite bottle of wine that I didn't even know I had," she said.
It had previously been claimed Cruise and Prepon first went on a date at the Manor Hotel in Los Angeles last November and the actor - who was previously married to Mimi Rogers, Nicole Kidman and Katie Holmes - was instantly smitten by her.
Prepon previously dated Malcolm in the Middle actor Chris Masterson before their reported split in 2012.