Awaiting funds, PGIMER yet to start trial of Covid vaccine-mixing

Published on Jun 27, 2022 02:19 AM IST

The PGIMER study, sponsored by ICMR, aims to discover how a person fully vaccinated with either Covishield or Covaxin responds to a booster of the other Covid vaccine

PGIMER has not yet start trial of Covid vaccine-mixing due to a delay in funds. (AP)
PGIMER has not yet start trial of Covid vaccine-mixing due to a delay in funds. (AP)
ByMandeep Kaur Narula, Chandigarh

The Post Graduate Institute of Medical Education and Research (PGIMER) is yet to start the clinical trials to find out if mixing vaccines for the booster dose is more effective than administering the same one even after six months of getting the approvals.

The Drugs Controller General of India (DCGI) had given the approval to conduct clinical trials in January this year, but the Centre is yet to release funds to the institute for the trials.

The study, which is sponsored by Indian Council of Medical Research (ICMR), aims to discover how a person fully vaccinated with either Covishield or Covaxin responds to a booster of the other vaccine (heterologous vaccination). It will also compare how people respond to a third dose of the same vaccine (homologous vaccination).

“The study is an investigator-initiated (academic) Phase 4 trial, authorization of which was given in January 2022. In the study, we were supposed to vaccinate 1028 healthy males or females, with 18 years of age or above. The purpose was to administer a third dose of Covaxin to those people who had taken two doses of Covishield, at least 12 months before, and vice versa”, said Dr Madhu Gupta, professor, Community Medicine and School of Public Health, and principal investigator of the project.

She added, “Though the DCGI had approved the project, the ICMR and central government had not released the funds for the study. Due to delay in funds, the project, which was supposed to take around a year for completion, has been delayed for six months. We will start the project as soon as we get the funds.”

India is presently using the same vaccine (primary vaccine) for precautionary, or booster dose as experts await data on mixing of vaccines among the Indian population.

Three more medical colleges in the country were conducting the same research while the preliminary scientific evidence submitted by the Christian Medical College, Vellore, to the DCGI in march this year, revealed that administering Covishield after two doses of Covaxin boosts immunity by 6 times.

In addition to Covishield and Covaxin mixing study, effects of mixing Corbevax, Covavax and Biotech’s intranasal vaccine is also being studied.

Close Story

Less time to read?

Try Quickreads

  • Former Mumbai zonal director of the Narcotics Control Bureau Sameer Wankhede, who got a clean chit from the Mumbai district caste certificate verification committee, at the National Commision for Scheduled Castes, in New Delhi, on Aug 16. (PTI)

    Got death threat on Twitter for FIR against Nawab Malik, Sameer Wankhede to cops

    Former Narcotics Control Bureau officer Sameer Wankhede on Thursday complained to the Goregaon police that he had received a death threat on Twitter for filing a defamation case against Nationalist Congress Party leader Nawab Malik. Deputy commissioner of police of Zone-11, Vishal Thakur, said that they have received information about the threat to Wankhede, an Indian Revenue Service officer, and are verifying the complaint before registering a first information report (FIR).

  • For representational purposes only. (Getty Images/iStockphoto)

    UKSSSC paper leak: Uttarakhand STF makes first arrest in Uttar Pradesh

    The special task force of the Uttarakhand police on Friday made the first arrest from Uttar Pradesh in connection with the Uttarakhand subordinate service selection commission (UKSSC) paper leak case, a senior police official said. A resident of Dhampur in Bijnor district, Junior engineer Lalit Raj Sharma was associated with an “inter-state cheating mafia” based in Uttar Pradesh. “He (Lalit) was an important link between mastermind Rawat and the cheating mafia of Uttar Pradesh. His arrest is a major success for us,” the STF SSP said.

  • Screengrab of video shared by ANI: AAP workers outside Manish Sisodia's house being taken into custody by the Delhi Police.

    Amid CBI raids, AAP workers detained outside Manish Sisodia home | Video

    A group of Aam Aadmi Party workers were on Friday detained by the Delhi Police outside deputy chief minister Manish Sisodia's residence after they gathered to protest the raids launched by the Central Bureau of Investigation over the national capital's excise policy. A video shared by news agency ANI showed cops taking several AAP workers to custody who were gathered outside Sisodia's house.

  • Mumbai: A building in Borivali West collapses on Friday, August 19.

    4-storey building in Mumbai's Borivali West collapses; no casualties reported

    A four-storey building collapsed in Mumbai's Borivali area on Friday. At least eight fire engines and fire brigade personnel have rushed to the spot, reported PTI quoting the Brihanmumbai Municipal Corporation. The Gitajali Building in Saibaba Nagar of Boriwali West collapsed around 12.34 pm. Officials said that the building had already been vacated after the BMC declared it as a dilapidated structure. Mumbai fire brigade has declared the collapse as L-2 level.

  • Over 60 lakh people had accessed BMTC buses on August 15 in Bengaluru. 

    Over 60 L people in Bengaluru travelled in BMTC free buses on August 15

    On August 15, Bengaluru Metropolitan Transport Corporation celebrated the 25th anniversary and a record number of commuters had accessed the free bus rides that were offered by the public transport. The sharp increase in the number of people who used public transport buses on August 15 has also raised a question of BMTC ticket prices on normal days.

Story Saved
Saved Articles
My Reads
Sign out
New Delhi 0C
Friday, August 19, 2022
Start 15 Days Free Trial Subscribe Now