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Noise could be used to treat AIDS

EMINENT SCIENTIST and Professor at Physics Department of Banaras Hindu University Prof TV Ramakrishnan said that the properties of noise could be effectively used to treat AIDS disease in future.
None | By HT Correspondent, Varanasi
PUBLISHED ON MAR 24, 2006 12:31 AM IST

EMINENT SCIENTIST and  Professor at Physics Department of Banaras Hindu University Prof TV Ramakrishnan said that the properties of noise could be effectively used to treat AIDS disease in future.

He was delivering a lecture on ‘Role of Noise in Gene Expression’ during the second day of three-day national seminar and workshop on ‘Bioinformatics and Computational Biology’ at Mahila Mahavidyalaya in Banaras Hindu University here on Thursday.

“The effect of noise on gene functioning is so immense that it can cause protein folding and decay of some proteins. This property of noise can be effectively used to treat AIDS disease,” he said.

He said cellular processes are random and described on how randomness (noise) play a role on different cellular processes at molecular level.

“It has been recently observed that the number of proteins produced at the cellular level has a distribution which is often long tailed,” he said and also talked about possible model for it and argued that this has a biological significance in specific ways. Prof Ramakrishnan also discussed direct experimental demonstration of noise and biological consequences of this noise.

Prof Rajiv Raman of Zoology Department in BHU presented his paper on ‘Genetic Polymorphism and Human Disease’. He said that single nucleotide alteration could cause diseases in humans.

“Small change in large number of genes can make a person susceptible to disease. Single nucleotide polymorphism is responsible for various diseases such as colon cancer, cleft, spina bifida etc.,” he said. Dr Devpriya Chaudhary from Centre of Biotechnology, Jawaharlal Nehru University (New Delhi) delivered a lecture on ‘Munnabhai MD: An Introduction to Molecular Simulation for Non Physicists’ whereas Prof Gita Subbarao from Biophysics Department at All India Institute of Medical Sciences (New Delhi), delivered a lecture on ‘Structural Biology and Structure Based Drug Design’.

Dr Andrew Lynn from Jawaharlal Nehru University dwelt upon ‘Introduction to Drug Design’. Prof SK Bhattacharya of Institute of Medical Sciences conducted the programme whereas seminar convener, Prof Uma Jaiswal welcomed the guests.

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