Longevity doctor reveals plaque buildup in arteries can be reversed; shares 4 steps to remove it in 12 months

Longevity expert Dr Vassily debunks the myth that arterial plaque can’t be reversed - and reveals a targeted strategy that may help reduce buildup.
If you’ve always assumed that once plaque settles into your arteries it’s there for good, you’re not alone - it’s a belief many people hold. But emerging insights suggest the opposite: with the right strategy, plaque can actually be reduced, lowering the long-term risk of heart disease and heart attacks. Focusing on arterial health isn’t just preventative; it can be transformative for your overall wellbeing.
Dr Vassily Eliopoulos - a longevity expert with an MD from Cornell University and Co-Founder and Chief Medical Officer of Longevity Health, widely known as Dr Vass - explains that, contrary to popular belief, arterial plaque buildup can in fact be reversed with a targeted approach.
In an Instagram video posted on July 25, the longevity specialist stresses the importance of identifying the root cause for your plaque formation - and outlines targeted ways to reverse it.
Cause of most heart attacks
Dr Vass notes that many cardiologists rarely clarify that most heart attacks aren’t actually triggered by artery-blocking calcium deposits - and that, in many cases, they can be reversed without stents or surgery.
He explains, “Most heart attacks happen from soft plaque that rupture, not arteries blocked by calcium buildup. You can have a normal stress test and still be at high risk. Surgery or stenting can fix the immediate symptom and can be life-saving when needed, but they do not fix the underlying disease process.”
The longevity expert stresses that preventing heart attacks begins with understanding their underlying cause and actively working to reverse plaque buildup.
How to reverse plaque buildup?
Dr Vass emphasizes, “New data (and the right testing) show that arterial plaque can be reduced, when you treat the root causes: inflammation, oxidative stress, and metabolic dysfunction. The key isn’t just lowering LDL. It’s reducing ApoB, calming vascular inflammation, optimising nitric oxide, and actually seeing what kind of plaque is forming: soft, calcified, or unstable.” He outlines four steps to identify the root cause:
1. Precision testing
- ApoB - measures true lipid particle load.
- High sensitivity CRP with Lp-PLA2 - Shows inflammation markers that fuel plaque formation.
- CCTA scan with Cleerly analysis - Identifies the type of plaque and where it is forming.
2. Targeted nutrition
Dr Vass advises adopting a Mediterranean-style diet rich in polyphenols, omega-3s, and fibre, while cutting out added sugars and ultra-processed foods that contribute to endothelial damage.
3. Therapeutic support
- Niacin and berberine - Can help in lowering ApoB and LPA
- Peptides like BPC157 and MOD C - May help reduce vascular inflammation and potentially improve mitochondrial function.
- IV nutrients like glutathione and arginine - Can help improve nitric oxide and vascular health.
4. Daily habits that move the needle
- Walking for five to 10 minutes after every meal.
- Zone 2 cardio at least three times a week.
- Prioritising at least seven and a half hours of sleep every night to lower cortisol and CRP.
The longevity doctor stresses, “Plaque doesn't reverse in weeks, but it's possible to obtain measurable results in six to 12 months using a targeted approach. This isn’t magic, it’s science, consistency, and a precision approach that can change the outcome without a scalpel.”
Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. It is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.
ABOUT THE AUTHOREshana SahaEshana Saha is a fresh face in lifestyle and cultural journalism, bringing a refined, multidisciplinary perspective to the intersection of entertainment, fashion and holistic wellbeing. With less than a year of professional experience, she has quickly adapted to high-pressure editorial environments and currently works full-time with HT Media. Prior to this, she interned for nearly six months with Hindustan Times’ entertainment and lifestyle vertical, where she gained hands-on experience in digital reporting, trend analysis and editorial storytelling. Based in New Delhi, Eshana specialises in comprehensive coverage of major cultural moments — from international film press tours to the curated aesthetics of global fashion showcases, award shows and music-centred events. She holds a Bachelor’s degree in English from St Xavier’s University, Kolkata, and a Master’s degree in English from the University of Delhi, equipping her with a strong academic foundation and a keen ability to deconstruct complex cultural trends into clear, high-impact narratives. Beyond the red carpet, Eshana has developed a growing focus on health and wellbeing reporting. She bridges the gap between celebrity-driven trends and practical, evidence-informed lifestyle advice, ensuring her work remains both aspirational and grounded in editorial rigour. She has extensively covered the health implications of Delhi’s air pollution crisis, while also playing a key role in amplifying expert-led insights on women’s health and mental wellbeing, helping translate complex medical perspectives into informed, impactful public awareness. An artist at heart, she explores multiple creative forms — from visual arts and music to culinary experiments — and brings a creative’s eye for nuance, texture and detail to every story. Whether analysing runway dynamics or examining emerging wellness movements, she remains committed to accuracy and the highest standards of contemporary journalistic ethics.Read More
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