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Gastroenterologist explains how drinking alcohol for only one night could also harm your body, trigger leaky gut

Gastroenterologist Dr Joseph Salhab warns that binge drinking can cause a 'leaky gut', letting harmful toxins enter the bloodstream.

Updated on: Jun 19, 2025, 08:14:45 IST
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Drinking alcohol may have become a symbol of letting go and having a good time with your friends, but even one night of drinking could harm your body. Even if you are an occasional drinker, the effects of alcohol could last up to 24 hours.

The more you drink, the worse gut leakage becomes; even a single night of binge drinking can cause a much more severe reaction. (Freepik)
The more you drink, the worse gut leakage becomes; even a single night of binge drinking can cause a much more severe reaction. (Freepik)

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Dr Joseph Salhab, MD (gastroenterology), often shares tips and facts about gut and kidney health on Instagram. In a video shared on June 18, he explained how drinking alcohol for only one night can ‘trigger a leaky gut, allowing bacterial toxins to enter the bloodstream and cause inflammation for 24 hours.’

What happens when you binge drink, even for one night?

Dr Salhab quoted a 2014 study to explain what happens to your body when you binge drink even for one night. Per the gastroenterologist, the research found that just one night of binge drinking can seriously mess with your gut.

He wrote, “It essentially makes your intestines ‘leaky’, allowing harmful bacterial toxins to escape and get into your bloodstream. The study clearly showed that the more you drank, the worse this gut leakage became, with a single night of binge drinking causing a much more severe reaction.”

What is leaky gut?

According to the gastroenterologist, there is no disease called ‘leaky gut’. “It describes a phenomenon that can happen with certain other gut diseases or chemical toxins, such as alcohol,” he explained.

“The term ‘leaky gut’ is often misused on social media. It is a real medical phenomenon where increased intestinal permeability occurs as a result of disease processes. In certain conditions like celiac disease, inflammatory bowel disease (IBD), and even critical illness or infections, the gut lining can become compromised, allowing larger molecules to pass through – a phenomenon sometimes referred to as ‘leaky gut’ in popular media,” Dr Joseph added.

Per the expert, while the term itself is often oversimplified or misapplied, the underlying pathophysiology is very real and well-documented in medical literature.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

  • Krishna Pallavi Priya
    ABOUT THE AUTHOR
    Krishna Pallavi Priya

    Krishna Priya Pallavi is a journalist with over 9 years of experience, covering health, fashion, pop culture, travel, wellness, entertainment, festivals, mental health, art, decor, fitness, and sex and relationships. She is an alumna of the Indian Institute of Mass Communication (IIMC), Dhenkanal, and holds an undergraduate degree in Journalism and Mass Communication from Guru Gobind Singh Indraprastha University, Delhi. Her strong academic foundation informs her analytical and detail-oriented approach to storytelling, helping her uncover stories where none seem to exist. Before joining Hindustan Times, Pallavi worked with some of India’s leading media organisations. She spent close to three years at India Today, where she honed her newsroom skills and developed a sharp editorial sensibility. She also worked for over a year and a half at Vagabomb, ScoopWhoop’s feminist digital platform, where she explored stories through a gender-sensitive, socially aware lens. Pallavi has a deep interest in global fashion trends and international fashion seasons, and enjoys interviewing celebrities and tracking pop culture movements—interests that frequently translate into engaging, reader-friendly stories. Alongside lifestyle and entertainment, she has a keen eye for impactful health and wellness journalism, regularly interacting with doctors, designers, and digital content creators to bring nuance and credibility to her work. Born and raised in Haryana, Pallavi remains deeply connected to her ancestral roots in Odisha. Her ability to spot fresh angles brings curiosity and depth to stories she pursues. When not chasing deadlines, she enjoys spending time with her dog, planning her next vacation, reading, running new trails, and discovering new destinations.Read More

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