Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.(Unsplash)
Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.(Unsplash)

Study: Antibiotics not needed after most sinus surgeries

Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.
By Asian News International | Posted by Shivani Kale | Boston
UPDATED ON JAN 06, 2021 03:14 PM IST

A randomized controlled trial held by Massachusetts Eye and Ear hospital studied about the difference in infection rates of ‘sinus’ and discovered that antibiotics increased gastrointestinal side effects in various patients.

Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.

The findings published in IFAR: International Forum of Allergy & Rhinology shows that patients who underwent endoscopic sinus surgery had no differences in outcomes including symptoms and infections whether they took an antibiotic or placebo after surgery.

The only reported difference in outcomes was in side effects, with patients in the antibiotic group 10 times more likely to report symptoms like diarrhea.

Study’s co-senior author Eric H. Holbrook, MD, director of the Division of Rhinology at Mass Eye and Ear and Associate Professor of Otolaryngology-Head and Neck Surgery at Harvard Medical School said, “For routine sinus surgery, antibiotics are unnecessary and may cause more complications like gastrointestinal side effects.”

The researchers embarked on a randomized placebo-controlled trial in 2013 when they started enrolling patients at Mass Eye and Ear undergoing uncomplicated endoscopic sinus surgery.

Patients without evidence of active infection during surgery were randomized to receive either a one-week regimen of an antibiotic or placebo afterwards.

A total of 77 patients (out of 134 enrolled) who met the study criteria were included in the final analysis: 37 received antibiotics and 40 did not. Patients were examined one week and six weeks after surgery.

Patients in both groups reported improvements in sinus symptoms after surgery, however, there were no statistically significant differences reported in rates of infection nasal symptoms between the two groups.

More than 24 per cent of patients in the antibiotic group reported diarrhea compared to 2.5 per cent in the placebo group.

While previous studies have looked at this issue of the utility of antibiotics after sinus surgery, there had been minimal, mixed data. This is the first study to have utilized a randomized trial to assess antibiotics on a one-week treatment duration on well-validated patient outcomes.

“Our findings suggest that otolaryngologists can rethink the practice of routinely prescribing antibiotics after endoscopic sinus surgery,” said study co-senior author Stacey T. Gray, MD, director of the Sinus Center at Mass Eye and Ear and an Associate Professor of Otolaryngology-Head and Neck Surgery at Harvard Medical School.

“Antibiotics should still be considered when the benefits outweigh the risks, including complex surgical procedures are performed or if the patient is at greater risk for developing an infection,” he added.

More than 250,000 sinus surgeries occur each year for treating chronic sinus infections that don’t respond to other medical treatment. In endoscopic sinus surgery, a scope and surgical tools are inserted into the nose to widen or open the normal drainage pathways that connect the sinuses to the nasal cavity.

It has long been debated whether antibiotics are routinely needed immediately after endoscopic sinus surgery to reduce the risk of postoperative infections and decrease swelling, and optimize patient outcomes.

This study only looked at routine endoscopic sinus surgery and not those that use dissolvable nasal packing, which can be a future area of study.

(This story has been published from a wire agency feed without modifications to the text.)

Follow more stories on Facebook and Twitter

SHARE THIS ARTICLE ON
app
Close
World chess champion Viswanathan Anand of India at the FIDE World Chess Championship in Moscow, Russia.
World chess champion Viswanathan Anand of India at the FIDE World Chess Championship in Moscow, Russia.

Human brain may get beaten by AI in chess, but not in memory: Study

ANI
PUBLISHED ON JAN 24, 2021 04:20 PM IST
In the last decades, Artificial Intelligence has shown to be very good at achieving exceptional goals in several fields.
Close
A new study has found that deep sleep has an ancient, restorative power to clear waste from the brain which potentially includes toxic proteins that may lead to neurodegenerative disease.(ANI)
A new study has found that deep sleep has an ancient, restorative power to clear waste from the brain which potentially includes toxic proteins that may lead to neurodegenerative disease.(ANI)

Neurodegenerative diseases can be prevented by deep sleep

ANI
PUBLISHED ON JAN 24, 2021 03:44 PM IST
A new study has found that deep sleep has an ancient, restorative power to clear waste from the brain which potentially includes toxic proteins that may lead to neurodegenerative disease.
Close
A new study has found that gene-editing techniques like CRISPR-Cas hold the power to rectify inherited retinal degenerative mutations, which are the primary cause of blindness.(ANI)
A new study has found that gene-editing techniques like CRISPR-Cas hold the power to rectify inherited retinal degenerative mutations, which are the primary cause of blindness.(ANI)

Gene editing techniques helpful in retinal degeneration treatment

ANI
PUBLISHED ON JAN 24, 2021 10:43 AM IST
A new study has found that gene-editing techniques like CRISPR-Cas hold the power to rectify inherited retinal degenerative mutations, which are the primary cause of blindness.
Close
Health workers prepare to administer the Oxford/AstraZeneca coronavirus disease (COVID-19) vaccine at an NHS vaccination centre in York, Britain, January 22, 2021. REUTERS/Lee Smith(REUTERS)
Health workers prepare to administer the Oxford/AstraZeneca coronavirus disease (COVID-19) vaccine at an NHS vaccination centre in York, Britain, January 22, 2021. REUTERS/Lee Smith(REUTERS)

Dramatic changes to radiotherapy treatments in England due to Covid-19

ANI
PUBLISHED ON JAN 23, 2021 10:18 AM IST
The new research, led by the University of Leeds, with Public Health England and the Royal College of Radiologists, reveals that there was a decrease in radiotherapy treatment courses of 19.9% in April, 6.2% in May, and 11.6% in June 2020, compared with the same months the previous year.
Close
An Indian-origin expert at the University of Birmingham has led an international study which finds that patients’ chances of survival after cancer surgery is strongly linked with the standard of post-operative hospital care.(Unsplash)
An Indian-origin expert at the University of Birmingham has led an international study which finds that patients’ chances of survival after cancer surgery is strongly linked with the standard of post-operative hospital care.(Unsplash)

Indian-origin expert leads UK study on cancer survival chances

PTI
PUBLISHED ON JAN 22, 2021 06:06 PM IST
An Indian-origin expert at the University of Birmingham has led an international study which finds that patients’ chances of survival after cancer surgery is strongly linked with the standard of post-operative hospital care.
Close
Spinal cord injuries in humans, often caused by sports or traffic accidents, leave them paralyzed because not all of the nerve fibers that carry information between muscles and the brain are able to grow back.(Unsplash)
Spinal cord injuries in humans, often caused by sports or traffic accidents, leave them paralyzed because not all of the nerve fibers that carry information between muscles and the brain are able to grow back.(Unsplash)

German scientists make paralyzed mice walk again

Reuters, Germany
PUBLISHED ON JAN 22, 2021 03:19 PM IST
German researchers have enabled mice paralyzed after spinal cord injuries to walk again, re-establishing a neural link hitherto considered irreparable in mammals by using a designer protein injected into the brain.
Close
 (HT llustration: Gajanan Nirphale)
(HT llustration: Gajanan Nirphale)

In her element: Talking to theoretical physicist Rohini M Godbole

PUBLISHED ON JAN 22, 2021 03:04 PM IST
Godbole, who recently received the Order of Merit from France, has dedicated her life to the pure sciences, and to bringing more women into the field. Why is that so crucial? Because what you study is partly defined by who you are, she says.
Close
Colorized scanning electron micrograph of an apoptotic cell (green) infected with SARS-COV-2 virus particles (yellow), also known as novel coronavirus, isolated from a patient sample(REUTERS)
Colorized scanning electron micrograph of an apoptotic cell (green) infected with SARS-COV-2 virus particles (yellow), also known as novel coronavirus, isolated from a patient sample(REUTERS)

Study sheds light on role played by immune system's T-cells against coronavirus

PTI, Los Angeles
PUBLISHED ON JAN 22, 2021 02:45 PM IST
In particular, they said "memory" CD8 T cells are important for protecting the body from reinfection against many viruses.
Close
A new study has found out that Transcranial Direct Current Stimulation (tDCS), which is a non-invasive way of stimulating the brain over the Wernicke's area, may lead to new assistive neurotechnologies for the rehabilitation of people with cognitive disorders in future.(ANI)
A new study has found out that Transcranial Direct Current Stimulation (tDCS), which is a non-invasive way of stimulating the brain over the Wernicke's area, may lead to new assistive neurotechnologies for the rehabilitation of people with cognitive disorders in future.(ANI)

Direct current stimulation over brain's Wernicke area can help learning words

ANI
PUBLISHED ON JAN 22, 2021 02:02 PM IST
A new study has found out that Transcranial Direct Current Stimulation (tDCS), which is a non-invasive way of stimulating the brain over the Wernicke's area, may lead to new assistive neurotechnologies for the rehabilitation of people with cognitive disorders in future.
Close
Scientists know that SARS-CoV-2 binds the ACE2 receptor on the surface of human cells, after which it enters the cell through a process known as endocytosis.(AFP)
Scientists know that SARS-CoV-2 binds the ACE2 receptor on the surface of human cells, after which it enters the cell through a process known as endocytosis.(AFP)

New study explains how SARS-CoV-2 may seize human cells

ANI, Washington
PUBLISHED ON JAN 22, 2021 10:03 AM IST
The findings also highlight that the possibilities could potentially serve as targets for new therapies for patients with Covid-19, although validation in cells and animal models is needed.
Close
Representational image(Unsplash)
Representational image(Unsplash)

Behind those dancing robots, scientists had to bust a move

AP
PUBLISHED ON JAN 21, 2021 11:46 PM IST
Behind those dancing robots, scientists had to bust a move
Close
A KAIST team's mathematical modelling has revealed that efficient brain circuitry develops spontaneously by showing that the topographic tiling of cortical maps originates from bottom-up projections from the periphery.(ANI)
A KAIST team's mathematical modelling has revealed that efficient brain circuitry develops spontaneously by showing that the topographic tiling of cortical maps originates from bottom-up projections from the periphery.(ANI)

Study reveals how efficient brain circuitry develops spontaneously

ANI
PUBLISHED ON JAN 20, 2021 04:20 PM IST
A KAIST team's mathematical modelling has revealed that efficient brain circuitry develops spontaneously by showing that the topographic tiling of cortical maps originates from bottom-up projections from the periphery.
Close
Immunotherapies are cancer drugs that essentially block the "don't-eat-me" signal coming from cancer and allow the immune-system to kill it. (Representative Image)(ANI)
Immunotherapies are cancer drugs that essentially block the "don't-eat-me" signal coming from cancer and allow the immune-system to kill it. (Representative Image)(ANI)

Researchers find how cancer can be killed by body's own immune system

ANI
PUBLISHED ON JAN 17, 2021 03:12 PM IST
In a previous study, scientists at the Cancer Research Center and the University of Missouri developed a genetically distinct and non-toxic strain of salmonella called CRC2631 to select and kill cancer cells.
Close
Painters refurbish the NASA logo on the Vehicle Assembly Building at the Kennedy Space Center in Florida.(AFP)
Painters refurbish the NASA logo on the Vehicle Assembly Building at the Kennedy Space Center in Florida.(AFP)

NASA test of mega Moon rocket engines cut short

AFP
PUBLISHED ON JAN 17, 2021 12:54 PM IST
  • Despite being cut short, NASA said the test of the RS-25 engines had provided valuable information for the planned missions.
Close
Space Launch System's hot fire test, expected to begin at 5 pm(@NASA/Twitter )
Space Launch System's hot fire test, expected to begin at 5 pm(@NASA/Twitter )

NASA's Boeing moon rocket set for 'once-in-a-generation' ground test

Reuters, Washington
PUBLISHED ON JAN 16, 2021 07:33 PM IST
The expendable super heavy-lift SLS is three years behind schedule and nearly $3 billion over budget.
Close
SHARE
Story Saved
OPEN APP