Music may be the key to treat epilepsy: Study
The brains of people with epilepsy appear to react to music differently from the brains of those who do not have the disorder, a finding that could lead to new therapies to prevent seizures, according to new research.Updated: Aug 11, 2015 11:06 IST
The brains of people with epilepsy appear to react to music differently from the brains of those who do not have the disorder, a finding that could lead to new therapies to prevent seizures, according to new research. "We believe that music could potentially be used as an intervention to help people with epilepsy," said Christine Charyton, from The Ohio State University Wexner Medical Centre.
Approximately 80% of epilepsy cases are what is known as temporal lobe epilepsy, in which the seizures appear to originate in the temporal lobe of the brain, researchers said. Music is processed in the auditory cortex in this same region of the brain, which was why Charyton wanted to study the effect of music on the brains of people with epilepsy.
Charyton and her colleagues compared the musical processing abilities of the brains of people with and without epilepsy using an electroencephalogram, where electrodes are attached to the scalp to detect and record brainwave patterns. They collected data from 21 patients who were in the epilepsy monitoring unit at The Ohio State University Wexner Medical Centre between September 2012 and May 2014.
The researchers recorded brainwave patterns while patients listened to 10 minutes of silence, followed by either Mozart's Sonata in D Major, Andante Movement II (K448) or John Coltrane's rendition of My Favourite Things, a second 10-minute period of silence, the other of the two musical pieces and finally a third 10-minute period of silence. The order of the music was randomised, meaning some participants listened to Mozart first and other participants listened to Coltrane first.
Researchers found significantly higher levels of brainwave activity in participants when they were listening to music. More important, said Charyton, brainwave activity in people with epilepsy tended to synchronise more with the music, especially in the temporal lobe, than in people without epilepsy. "We were surprised by the findings," said Charyton.
"We hypothesised that music would be processed in the brain differently than silence. We did not know if this would be the same or different for people with epilepsy," she said.