World-first techniques for predicting breast cancer risk from mammograms that were developed could revolutionise breast screening by allowing it to be tailored to women at minimal extra cost.(Unsplash)
World-first techniques for predicting breast cancer risk from mammograms that were developed could revolutionise breast screening by allowing it to be tailored to women at minimal extra cost.(Unsplash)

New mammogram measures of breast cancer risk could revolutionise screening

World-first techniques for predicting breast cancer risk from mammograms that were developed in Melbourne could revolutionise breast screening by allowing it to be tailored to women at minimal extra cost.
By Asian News International | Posted by Shivani Kale | Washington
PUBLISHED ON DEC 23, 2020 03:01 PM IST

World-first techniques for predicting breast cancer risk from mammograms that were developed in Melbourne could revolutionise breast screening by allowing it to be tailored to women at minimal extra cost.

Published in the International Journal of Cancer, the University of Melbourne-led study found two new mammogram-based measures of risk.

When these measures are combined, they are more effective in stratifying women in terms of their risk of breast cancer than breast density and all the known genetic risk factors.

Researchers say if successfully adopted, their new measures could substantially improve screening, make it more effective in reducing mortality and less stressful for women, and therefore encourage more to be screened. They could also help address the problem of dense breasts.

Since the late 1970s, scientists have known that women with denser breasts, which shows up on a mammogram as having more white or bright regions, are more likely to be diagnosed with breast cancer and to have it missed at the screening.

Collaborating with Cancer Council Victoria and BreastScreen Victoria, University of Melbourne researchers were the first to study other ways of investigating breast cancer risk using mammograms.

Using computer programs to analyse mammogram images of large numbers of women with and without breast cancer, they found two new measures for extracting risk information. Cirrocumulus is based on the image’s brightest areas and Cirrus on its texture.

First, they used a semi-automated computer method to measure density at the usual, and successively higher levels of brightness to create Cirrocumulus.

They then used artificial intelligence (AI) and high-speed computing to learn about new aspects of the texture (not brightness) of a mammogram that predict breast cancer risk and created Cirrus.

When their new Cirrocumulus and Cirrus measures were combined, they substantially improved risk prediction beyond that of all other known risk factors.

Lead researcher and University of Melbourne Professor John Hopper said that in terms of understanding how much women differ in their risks of breast cancer, these developments could be the most significant since the breast cancer genes BRCA1 and BRCA2 were discovered 25 years ago.

“These measures could revolutionise mammographic screening at little extra cost, as they simply use computer programs. The new measures could also be combined with other risk factors collected at screening, such as family history and lifestyle factors, to provide an even stronger and holistic picture of a woman’s risk,” Professor Hopper said.

“Tailored screening - not ‘one size fits all’ - could then be based on accurately identifying women at high, as well as low, risk so that their screening can be personalised. Given mammography is now digital, and our measures are now computerised, women could be assessed for their risk at the time of screening - automatically - and given recommendations for their future screening based on their personal risk, not just their age,” Hopper added.

Professor Hopper said this information could be used to ease pressure on BreastScreen, which had to close for a period during the COVID-19 pandemic and is looking for ways to best handle the backlog while continuing to provide a valuable service with limited resources.

He said the current breakthrough could not have occurred without the extraordinary support his mammogram research had received from the National Breast Cancer Foundation, starting with its first funding round more than 20 years ago.

“Only around 55 per cent of Australian women aged 50-74 currently present for screening aimed at detecting breast cancers early,” he said.

“Knowing that screening could also give an accurate risk prediction could encourage more women to take up the offer of free screening. Women with high risk based on their mammogram would also benefit greatly from also knowing their genetic risk,” he added.

Adjunct Associate Professor Helen Frazer, Clinical Director of St Vincent’s BreastScreen Melbourne, said that improvements in assessing a woman’s risk of breast cancer would be transformative for screening programs.

“Using AI developments to assess risk and personalise screening could deliver significant gains in the fight against breast cancer,” Adjunct Associate Professor Frazer said.

(This story has been published from a wire agency feed without modifications to the text. Only the headline has been changed.)

Follow more stories on Facebook and Twitter

SHARE THIS ARTICLE ON
Close
Blood tests can offer early indicator of severe Covid-19? Here's what study says(Photo by National Cancer Institute on Unsplash)
Blood tests can offer early indicator of severe Covid-19? Here's what study says(Photo by National Cancer Institute on Unsplash)

Blood tests can offer early indicator of severe Covid-19? Here's what study says

ANI
UPDATED ON MAR 02, 2021 06:09 PM IST
As per a recent study, blood tests can help doctors predict whether a coronavirus patient requires care in the intensive care unit or requires ventilator support or is suffering from severe Covid-19 that could lead to death
Close
High fat diets may over-activate destructive heart disease protein: Study(Photo by Robina Weermeijer on Unsplash)
High fat diets may over-activate destructive heart disease protein: Study(Photo by Robina Weermeijer on Unsplash)

High fat diets may over-activate destructive heart disease protein: Study

ANI
UPDATED ON MAR 02, 2021 05:53 PM IST
A new research has found that a high-fat diet can cause damage to the muscle cells that make up our hearts by causing a normally harmless protein, Nox2, to become overactive
Close
The skeleton of Little Foot is seen in Sterkfontein, South Africa, in this undated handout photo, obtained by Reuters on March 1, 2021.(Reuters)
The skeleton of Little Foot is seen in Sterkfontein, South Africa, in this undated handout photo, obtained by Reuters on March 1, 2021.(Reuters)

Painstaking study of 'Little Foot' fossil sheds light on human origins

Reuters
PUBLISHED ON MAR 02, 2021 02:58 PM IST
Little Foot's species blended ape-like and human-like traits and is considered a possible direct ancestor of humans.
Close
Representational Image(Unsplash)
Representational Image(Unsplash)

Low cost, high efficiency mask design presented by Oxford study

ANI, Washington Dc
PUBLISHED ON MAR 02, 2021 02:12 PM IST
The Covid-19 crisis has increased demand for respiratory masks, with various models of DIY masks becoming popular alongside the commercially available N95. The utility of such masks is primarily based on the size of aerosols that they are capable of filtering out and how long they can do so effectively.
Close
Representational Image(Unsplash)
Representational Image(Unsplash)

Here's why using cannabis to treat migraine could up risk of rebound headaches

ANI, Washington Dc
PUBLISHED ON MAR 02, 2021 02:11 PM IST
The study found that people who were using cannabis had significantly increased odds of also having medication overuse headache, or rebound headache, compared to people who were not using cannabis.
Close
Taapsee Pannu(Instagram)
Taapsee Pannu(Instagram)

'Let's talk periods': Taapsee Pannu addresses 'the elephant in the room'

By hindustantimes.com | Edited by Alfea Jamal, Hindustan Times, Delhi
UPDATED ON MAR 02, 2021 11:44 AM IST
On Monday, Taapsee Pannu hopped on to her Instagram and shared a ruminative video that sees her addressing the taboo surrounding menstruation, which she referred to as 'the elephant in the room'.
Close
Esha Gupta shares new fitness post(Instagram/egupta)
Esha Gupta shares new fitness post(Instagram/egupta)

Esha Gupta's extreme stretch amazes everyone, Masaba's comment wins the day

By Nishtha Grover, Delhi
PUBLISHED ON MAR 02, 2021 10:27 AM IST
  • Esha Gupta recently shared a fitness post nailing an extreme stretch and left her audience speechless. We are in awe of the actor too.
Close
Climate extremes seen harming unborn babies in Brazil's Amazon(Pexels)
Climate extremes seen harming unborn babies in Brazil's Amazon(Pexels)

Climate change is harming unborn babies in Brazil, says research

Reuters
PUBLISHED ON MAR 02, 2021 07:46 AM IST
The findings of a new research show a connection between extreme rains and lower birth weights and even premature births in Brazil's Amazon region.
Close
Monday motivation: Malaika Arora shares steps-benefits of Anulom Vilom Pranayama(Instagram/malaikaaroraofficial)
Monday motivation: Malaika Arora shares steps-benefits of Anulom Vilom Pranayama(Instagram/malaikaaroraofficial)

Monday motivation: Malaika Arora shares steps-benefits of Anulom Vilom Pranayama

By Zarafshan Shiraz
UPDATED ON MAR 01, 2021 06:24 PM IST
  • Yoga enthusiast Malaika Arora stresses on the importance of breathing for overall wellness, lays Monday motivation by taking fitness freaks through the steps and benefits of Anulom Vilom Pranayama or Alternate Nostril Breathing exercises | Watch
Close
The photo of Jonah Hill posted by The Daily Mail(Instagram)
The photo of Jonah Hill posted by The Daily Mail(Instagram)

Jonah Hill shares body acceptance post, calls out daily for shaming him

By hindustantimes.com | Edited by Alfea Jamal, Hindustan Times, Delhi
UPDATED ON MAR 01, 2021 05:53 PM IST
American actor and comedian Jonah Hill was the subject of one such article by a leading British daily and the two time Oscar nominee decided to take it in his stride, and turned it into a post about body positivity and acceptance.
Close
Karisma Kapoor flaunts lean figure(Instagram/therealkarismakapoor )
Karisma Kapoor flaunts lean figure(Instagram/therealkarismakapoor )

Karisma Kapoor starts new month with fitness post, flaunts lean figure

By Nishtha Grover, Delhi
PUBLISHED ON MAR 01, 2021 02:28 PM IST
  • Karisma Kapoor recently took to Instagram to flaunt her toned midriff and inspired us to start the month on a fitter note and take care of our health.
Close
A team of researchers suggests three ways to more fairly and effectively distribute the vaccine so that people in poor countries get the vaccine as soon as possible.(Pixabay)
A team of researchers suggests three ways to more fairly and effectively distribute the vaccine so that people in poor countries get the vaccine as soon as possible.(Pixabay)

Researchers shed light on why Covid-19 vaccine distribution methods fall short

ANI, New York [us]
PUBLISHED ON MAR 01, 2021 01:31 PM IST
Several proposals have emerged on how to distribute the Covid-19 vaccine, but they fall short in ensuring that the vaccine is distributed fairly.
Close
Long-term, heavy coffee consumption - six or more cups a day - can increase the number of lipids (fats) in your blood to significantly heighten your risk of cardiovascular disease (CVD).(Pixabay)
Long-term, heavy coffee consumption - six or more cups a day - can increase the number of lipids (fats) in your blood to significantly heighten your risk of cardiovascular disease (CVD).(Pixabay)

Study: Too much coffee consumption can be detrimental for your heart health

ANI, Adelaide [australia]
PUBLISHED ON MAR 01, 2021 01:05 PM IST
Too much coffee could be detrimental for your heart health and could cause heart-related issues, suggest the findings of a new study.
Close
Shilpa Shetty shares steps of Yoga’s Paschimottanasana as perfect remedy for Monday blues(Instagram/theshilpashetty)
Shilpa Shetty shares steps of Yoga’s Paschimottanasana as perfect remedy for Monday blues(Instagram/theshilpashetty)

Shilpa Shetty hails Yoga’s Paschimottanasana as perfect remedy for Monday blues

By Zarafshan Shiraz
UPDATED ON MAR 01, 2021 12:59 PM IST
  • Shilpa Shetty Kundra shows how to let the positive Monday energy wash down over you by giving ‘the spine, shoulders, and hamstrings that much-needed stretch’ with Yoga’s Forward Bend Pose or Paschimottanasana | Watch
Close
In the quest for clearer, supple skin!
In the quest for clearer, supple skin!

In the quest for clearer, supple skin!

By Swati Chaturvedi
PUBLISHED ON MAR 01, 2021 12:29 PM IST
Tried every lotion, potion and serum on earth to treat the problem but still can’t get rid of adult acne. You are not alone! It’s time to get to the root of the problem. In other words, knowing what’s causing your pimples can help you clear up your skin and keep breakouts at bay.
Close
SHARE
Story Saved
OPEN APP