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Cannabis may stop cancer spread

Cannabidiol, a compound found in hashish aka ganja, may stop breast cancer from spreading, says a study.

health and fitness Updated: Nov 21, 2007 13:22 IST

A chemical found in cannabis may stop breast cancer from spreading through the body and could be a non-toxic alternative to chemotherapy, scientists said.

There is a limited range of treatments available for aggressive forms of cancer such as chemotherapy, a drug treatment to kill cancer cells that can be effective but also extremely toxic and difficult for patients, said scientists.

Sean McAllister, lead researcher of The California Pacific Medical Centre Research Institute team, said: "The compound found in cannabis called 'cannabidiol' (CBD) offers the hope of a non-toxic therapy that could achieve the same results without any of the painful side effects."

CBD works by blocking the activity of a gene called Id-1, which is believed to be responsible for the aggressive spread of cancer cells away from the original tumour site creating what are known as 'secondaries'.

Past research has already shown that CBD can block aggressive human brain cancers. The new lab tests found that CBD had a similar effect on breast cancer cells, reported the online edition of Daily Mail.

Doctors, however, warn that smoking cannabis is unlikely to be effective, as sufficient quantities of CBD are not found in the leaf.

They have to be extracted and then concentrated to make a dose strong enough to kill cancer cells, the scientists said, adding that the research is at a very early stage.

The findings will need to be followed up with clinical trials in humans to see if the CBD is safe, and whether the beneficial effects can be replicated, scientists said.

First Published: Nov 21, 2007 12:41 IST