Engineered 'glue' allows wounds to heal faster
It may sound like something out of Asimov's Science Fiction magazine, but researchers in Switzerland have created a substance designed to help wounds heal faster, from minor cuts to broken bones.Updated: Feb 25, 2014 15:40 IST
It may sound like something out of Asimov's Science Fiction magazine, but researchers in Switzerland have created a substance designed to help wounds heal faster, from minor cuts to broken bones.
The substance, referred to as, "engineered growth factor," works by, "remaining near the damaged tissue longer than it normally would".
Growth factors are defined as proteins produced naturally by animals. These factors have a variety of uses in the body, from contributing to fetal development to healing skin gashes and broken bones. When the body is injured, growth factors signal certain cells to surround the wound and promote healing.
While growth factors are essential in the healing of wounds, it is difficult to get such proteins "stick where they are needed". Long-lasting, engineered "glue" could subsequently benefit those with chronic wounds stemming from diabetes or immune system deficiencies.
Jeffrey Hubbell, a professor of bioengineering at the Swiss Federal Institute of Technology in Lausanne (EPFL) and study co-author, noted that smaller doses are key to the effectiveness ofthe product, as previous experiments often resulted in growth factors going into "overdrive".
Piyush Koria, a professor of chemical and biomedical engineering at the University of south Florida, remarked that studies like these could get a higher number of growth-factor treatments into clinics. As of now, only two growth factors are used in clinical treatments, although studies have gone on for years.
"[Clinical researchers] all mention that delivery has been a big issue," Koria said. "Such treatments could also help treat burn victims. One reason even small third-degree burns are so hard to treat is that the cells that would release growth factors are simply not there anymore."
Koria admits he is still cautious about the work, as designing treatments using growth factors is "tricky". However, if the treatment is successful, doctors will have another option for patients regarding wound healing and reconstruction.
The new research was published in the February 21 issue of Science.
First Published: Feb 25, 2014 15:37 IST