O Dopa Mine
The chemicals in our bodies make us what we are…
The chemicals in our bodies make us what we are…

The Times Of India, June 6
This is probably what the famous balcony scene in Shakespeare’s Romeo and Juliet (Act 2, Scene 2) would be like if due credit was given to our hormones:
Juliet: O Romeo, Romeo! Wherefore art thou Romeo?
Romeo: What light through yonder window breaks? It is the east and Juliet is the sun. Or could it be that it is the adrenaline pounding in my blood?
Juliet: Ay me.
Romeo: She speaks. O speak again, bright angel, for ’tis clear your serotonin levels are elevated. Never have I beheld a maiden with more of the estrogen estradiol.
Juliet: ’Tis but thy name that is my enemy;
Thou art thyself, though not a Montague.
Romeo: Call me but love, and I’ll be new baptised;
Henceforth I never will be Romeo.
Juliet: O, be some other name!
What’s in a name? That which we call a rose
By any other name would smell as sweet.
Romeo: My name, dear saint, is hateful to myself,
Because it is an enemy to thee;
Call me Testosterone.
Juliet: O Testosterone, Testosterone! Wherefore art thou Testosterone?
Romeo: It is my lady, O, it is my love. O that I were the DARPP 32 protein, encoded by the PPP1R1B gene that I might touch her dopamine receptors.
Juliet: How camest thou hither, tell me, and wherefore?
The orchard walls are hard to climb.
Romeo: With phenylethylamine light wings did I o’er-perch these walls;
For stony limits cannot hold cortisol,
And what Testosterone can do that dares Testosterone attempt.
Juliet: Thou know’st the mask of night is on my face,
Else would a beta-endorphin bepaint my cheek.
Romeo: Lady, by yonder blessed moon I swear.
Juliet: O, swear not by the moon, the inconstant moon,
That monthly changes in her circled orb,
Lest thy love prove likewise variable.
Romeo: What shall I swear by?
Juliet: Do not swear at all;
Or, if thou wilt, swear by thy gracious dopamine
And I’ll believe thee. O gentle Testosterone,
If thou dost love, pronounce it.
Romeo: O love of my androgens, including D REA, testosterone and androstenedione…
Juliet: Well, do not swear: although I joy in thee,
I have no joy of this contract tonight:
It is too rash, too unadvised, too sudden; too much like a surge of norepinephrine.
Sweet, good night!
This bud of love, by hormone’s ripening breath,
May prove a beauteous flower when next we meet.
Good night! As sweet oxytocin
Come to thy heart as that within my breast!
Romeo: And vasopressin to thee. But wilt thou leave me so unsatisfied?
Juliet: What satisfaction canst thou have tonight?
Romeo: The exchange of thy hormones for mine. Thy endorphins for my enkephalins, my testosterone for thine estrogens.
Juliet: I gave thee mine before thou didst request it:
If that thy bent of love be honourable,
Thy purpose marriage, send me word tomorrow.
Romeo: Methinks me detects vasopressin aka the monogamy molecule kicking in. Thine words have activated my withdrawal symptoms, I feelest my prolactin levels rising, whilst my androgen receptors droppest. Adieu, O Dopa Mine…
Manas Chakravarty is Consulting Editor, Mint
The views expressed by the author are personal
ABOUT THE AUTHORManas ChakravartyThe PM’s speech in Toronto contained the analogy that while India and Canada growing separately would be a2 + b2, when joined together in friendship they would be (a+b)2 which equals a2 +2ab+b2, with the synergy giving an extra 2ab.Read More

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