California cardiologist with 20 years experience warns against negative impact of weight loss drugs on your metabolism

According to cardiologist Dr Sanjay Bhojraj, weight-loss medications may aid in losing weight but can negatively impact metabolism.
Weight loss drugs have become a huge part of the wellness trend and have been utilised by those struggling with losing weight for years. While there have been many discussions about their benefits and ill effects, Dr Sanjay Bhojraj is highlighting their impact on the metabolism.
On December 9, Dr Sanjay, a functional medicine doctor and board-certified interventional cardiologist with over 20 years of experience, shared a video on Instagram highlighting what weight loss drugs do to our metabolism.
Weight loss drugs and their impact on metabolism
Sharing a video, titled ‘Weight loss medications can help you lose weight…but no one talks about what they do to your metabolism after’, Dr Sanjay revealed that during the 20 years of practising cardiology, he has kept the same pattern in patients: they were ‘losing weight quickly on medication, but feeling worse on the inside.’
Explaining the reason behind the phenomenon, the cardiologist stated that it was because they were “exhausted, unfocused, anxious about weight returning, and confused about why their metabolism felt ‘slowed down’ even though the scale had dropped.”
According to the cardiologist, they tried eating less, adding more workouts, switching medications, pushing through fatigue, and even doubling down on routines that had worked in the past. However, nothing truly fixed the underlying issues for these patients.
The real reason: ‘Weight-loss medication changes your metabolic…’
The cardiologist shared in the post that after years of watching these patterns repeat, he understood the real missing link: “Weight-loss medication changes your metabolic signalling, and the only thing that worked long-term was rebuilding the systems those medications quiet down.”
How can one fix these issues? According to Dr Sanjay, everything shifted - 'their metabolism woke back up, energy returned, and weight stabilised without fear of rebounding - when patients started focusing on repairing their:
- Mitochondria
- Hormones
- Appetite pathways
- Energy rhythms
Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.
This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.
ABOUT THE AUTHORKrishna Pallavi PriyaKrishna Priya Pallavi is a journalist with over 9 years of experience, covering health, fashion, pop culture, travel, wellness, entertainment, festivals, mental health, art, decor, fitness, and sex and relationships. She is an alumna of the Indian Institute of Mass Communication (IIMC), Dhenkanal, and holds an undergraduate degree in Journalism and Mass Communication from Guru Gobind Singh Indraprastha University, Delhi. Her strong academic foundation informs her analytical and detail-oriented approach to storytelling, helping her uncover stories where none seem to exist. Before joining Hindustan Times, Pallavi worked with some of India’s leading media organisations. She spent close to three years at India Today, where she honed her newsroom skills and developed a sharp editorial sensibility. She also worked for over a year and a half at Vagabomb, ScoopWhoop’s feminist digital platform, where she explored stories through a gender-sensitive, socially aware lens. Pallavi has a deep interest in global fashion trends and international fashion seasons, and enjoys interviewing celebrities and tracking pop culture movements—interests that frequently translate into engaging, reader-friendly stories. Alongside lifestyle and entertainment, she has a keen eye for impactful health and wellness journalism, regularly interacting with doctors, designers, and digital content creators to bring nuance and credibility to her work. Born and raised in Haryana, Pallavi remains deeply connected to her ancestral roots in Odisha. Her ability to spot fresh angles brings curiosity and depth to stories she pursues. When not chasing deadlines, she enjoys spending time with her dog, planning her next vacation, reading, running new trails, and discovering new destinations.Read More
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