Cardiac surgeon breaks down whether melatonin use is linked to increased risk of heart failure
A new study links melatonin use with increased risk of heart disease, but does it really cause heart failure? Dr Yaranov explains what the study actually means.
A new American Heart Association study has raised concerns about a possible link between long-term melatonin use and a higher risk of heart failure. But does this mean taking melatonin can actually cause the heart to fail - or could it be pointing to deeper, underlying health issues?

Dr Dmitry Yaranov, a cardiologist and heart transplant surgeon, specialising in advanced heart failure, heart transplantation, and mechanical circulatory support, is breaking down whether melatonin use may be linked to a higher risk of heart failure. In an Instagram video posted on November 11, the cardiac surgeon addresses a new American Heart Association study linking melatonin use to heart failure, clarifying what the research actually found and what it means for users.
What did the study find?
Dr Yaranov states, “News came out this morning from a study presented at the American Heart Association that linked long-term melatonin use with higher risk of heart failure.” He then goes on to break down what the researchers examined and the key findings of their study.
The cardiac surgeon explains, “The researchers looked at more than 1,30,000 adults that had insomnia and followed for five years. Those who used melatonin had a 90% higher chance of developing heart failure, more hospitalisation, and the risk of dying from heart failure.”
Does melatonin really cause heart failure?
Dr Yaranov emphasises that the study’s findings show an association - not a direct cause-and-effect link - between melatonin use and heart failure. He explains, “The people who rely on melatonin every night have severe sleep disturbance, more stress, and underlying medical disease or sometimes underdiagnosed sleep apnea. And all of this can be independently increasing your cardiovascular risk factor.”
He stresses that melatonin, in itself, is not dangerous. The cardiac surgeon adds that to determine whether melatonin truly plays a role or is merely a marker of underlying health issues, further research - particularly well-designed randomised controlled trials - is needed.
However, he warns, “If you depend on melatonin every night just to sleep, your body is signaling something. It deserves evaluation. Sleep is the core part of heart health. Treat the cause, do not treat the symptom.”
Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. It is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.
ABOUT THE AUTHOREshana SahaEshana Saha is a fresh face in lifestyle and cultural journalism, bringing a refined, multidisciplinary perspective to the intersection of entertainment, fashion and holistic wellbeing. With less than a year of professional experience, she has quickly adapted to high-pressure editorial environments and currently works full-time with HT Media. Prior to this, she interned for nearly six months with Hindustan Times’ entertainment and lifestyle vertical, where she gained hands-on experience in digital reporting, trend analysis and editorial storytelling. Based in New Delhi, Eshana specialises in comprehensive coverage of major cultural moments — from international film press tours to the curated aesthetics of global fashion showcases, award shows and music-centred events. She holds a Bachelor’s degree in English from St Xavier’s University, Kolkata, and a Master’s degree in English from the University of Delhi, equipping her with a strong academic foundation and a keen ability to deconstruct complex cultural trends into clear, high-impact narratives. Beyond the red carpet, Eshana has developed a growing focus on health and wellbeing reporting. She bridges the gap between celebrity-driven trends and practical, evidence-informed lifestyle advice, ensuring her work remains both aspirational and grounded in editorial rigour. She has extensively covered the health implications of Delhi’s air pollution crisis, while also playing a key role in amplifying expert-led insights on women’s health and mental wellbeing, helping translate complex medical perspectives into informed, impactful public awareness. An artist at heart, she explores multiple creative forms — from visual arts and music to culinary experiments — and brings a creative’s eye for nuance, texture and detail to every story. Whether analysing runway dynamics or examining emerging wellness movements, she remains committed to accuracy and the highest standards of contemporary journalistic ethics.Read More
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