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Did you know the most powerful detox happens at night? Doctor explains why sleep is important

Updated on: Feb 26, 2026, 14:52:04 IST
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Sleep is divided into non-REM and REM cycles. (Unsplash)
Sleep is divided into non-REM and REM cycles. (Unsplash)

According to Dr Thomas Paloschi, sleep works like a medicine to detox the body and repair it. Losing sleep thus actively harms one's health. 

A good night’s sleep is an indispensable part of a healthy lifestyle. It is common knowledge that sleep is the time when the body heals itself after toiling through the day.

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Taking to Instagram on January 31, Dr Thomas Paloschi, a longevity medical doctor specialising in preventative age management and functional medicine, explained how it works, claiming sleep to be the most powerful “detox.

“Miss sleep and you don't just lose energy. You lose brain repair, memory consolidation, and emotional control,” he cautioned.

The brain’s clean-up system

While the body is in deep sleep, the brain activates a clearance pathway called the glymphatic system, noted Dr Paloschi.

It is a nightly rinse cycle for the brain, which involves the cerebrospinal fluid (CSF) flowing through the brain to wash away waste products such as protein buildups and toxins. The waste flows through the glymphatic vessels to the body’s circulation.

Why sleep is necessary

While the body is at rest while sleeping, the brain continues to function. However, there is one significant change: during sleep, the brain switches from performance mode to maintenance mode.

According to Dr Paloschi, chronic poor sleep is linked to:

  • Higher risk for brain ageing and dementia
  • Less emotional stability: more anxiety, low mood, irritability
  • Weaker memory and focus
  • Slower reaction time and higher accident risk

“Wake time creates micro-damage. Sleep is when the brain fixes it,” noted the physician. “Skip sleep often enough, and the damage starts to accumulate.”

Stages of sleep

Sleep runs in cycles of approximately 90 minutes each, and shifts between non-REM (rapid eye movement) and REM sleep. An individual gets more deep non-REM sleep in the first half of the night, and more REM sleep in the second half.

Therefore, if the sleep time is reduced from eight to six hours, one disproportionately loses more REM sleep, warned Dr Paloschi. A shorter sleep is not just less rest but less repair.

Different stages of sleep have different functions to perform.

  • Deep non-REM: stabilises what one has learned (protects new memory)
  • Stage 2 (spindles): upgrades learning capacity for the next day
  • REM: integrates emotion with memory (less emotional "charge")

How to sleep better

Dr Paloschi shares the following guidelines to improve sleep quality:

  1. Regularity (same timing)
    1. Keep wake time consistent (±30 to 60 min)
    2. Bedtime within 1 hour (approx) most nights
  2. Continuity (less fragmentation)
    1. Aim for sleep efficiency ≥85%
    2. Frequent awakenings/snoring screen for sleep apnea
  3. Quantity (enough total sleep)
    1. Most adults: 7 to 9 hours
    2. Avoid a chronic baseline of less than 7 hours
  4. Quality (real deep and REM)
    1. Don't cut the first half (deep sleep) or last 1 to 2 hours (REM)
    2. Limit alcohol at night and late caffeine consumption
    3. Sleep cave: cool, dark, quiet

“Sleep is biological maintenance. Miss it, and you miss your brain's nightly window for cleanup, repair, and recalibration,” stated the physician, adding that it is as important as medicine.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

  • Debapriya Bhattacharya
    ABOUT THE AUTHOR
    Debapriya Bhattacharya

    Debapriya Bhattacharya is a Content Producer at Hindustan Times. He started his career in 2022, working in newsrooms in beats like education, US news, trending stories, and entertainment. In his new role in the lifestyle desk, he seeks to deliver a balanced blend of research-driven reporting and creative storytelling from health and recipes to art and culture. Science, philosophy, food and pop culture are what pump his veins and help bring heart to his stories. Debapriya tries to see out subjects that will allow him and readers to explore new frontiers and improve the quality of life for all. The explorations can be both external and internal, as thoughts seek to be as chaotic as the greater universe. As a citizen of the world, Debapriya has been fascinated by the lives of people across the globe throughout time. His curiosity leads him to explore new linguistic and cultural landscapes to broaden his horizons and deepen his understanding of global narratives. Beyond the newsroom, Debapriya loves to participate in debate and theatre, spaces that he considers to be holy grounds for nuance and self-expression. A graduate from Ashutosh College, University of Calcutta, Debapriya completed his Master's degree from the same university in 2022. An ambiverted bibliophile, he loves his solitude as much as he adores stimulating conversations. And despite his reverence for tech, libraries continue to be his favourite place for research.Read More

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