Representative(Bloomberg)
Representative(Bloomberg)

IIT Roorkee to conduct research for identifying antiviral to tackle COVID-19

Indian Institute of Technology (IIT) Roorkee will conduct research on the identification of antiviral to treat COVID-19.
By Asian News International | Posted by Nandini | Dehradun
PUBLISHED ON MAY 29, 2020 08:46 AM IST

Indian Institute of Technology (IIT) Roorkee will conduct research on the identification of antiviral to treat COVID-19.

This development comes after a proposal led by Professor Pravindra Kumar has been given a go-ahead by the Science and Engineering Research Board (SERB).

“The study will identify small molecule inhibitors to target key viral replication enzymes- RNA dependent RNA polymerase (nsp12), viral proteases (Mpro and PL2pro) and the Methyltransferase or MTase (nsp14),” an official release said.

“These enzymes are virus-specific that are encoded with genetic material (RNA) of the viral pathogens. Virus-specific protease catalyses the cleavage of specific peptide bonds in viral polyproteins. The study will be funded under the intensification of Research in high-priority areas (IRHPA) under the Department of Science and Technology (DST),” it said.

The objective of the study is to identify antiviral molecules to combat COVID-19 and it will expedite the process of identification of drugs through an in-silico approach that is based on computer-aided simulation of their molecular structures.

“I would like to thank the Science and Engineering Research Board for reposing faith in us,” said Prof. Kumar, Department of Biotechnology, IIT Roorkee.

The groundwork of the research has already been prepared by the completion of in silico work based on high throughput virtual screening approach to assess the binding affinity of the Food and Drug Administration (FDA)-approved drugs targeting Mpro -- a viral protease.

The study will leverage a computer-based high throughput virtual screening approach to identify antiviral molecules from various compound libraries that will be validated for antiviral potential, the release said.

It will be conducted in collaboration with Prof. Shailly Tomar, Dept of Biotechnology, IIT Roorkee, and Dr Gaurav Sharma from the Indian Veterinary Research Institute (IVRI), Izatnagar who will aid in the assessment of the antiviral efficacy of the identified molecule to treat SARS-CoV2.

“This approach can be path-breaking in the identification of antiviral molecules to fight COVID-19,” said Prof. Ajit K Chaturvedi, Director, IIT Roorkee.

SHARE THIS ARTICLE ON
app
Close
NITRD Recruitment 2021.(HT File)
NITRD Recruitment 2021.(HT File)

NITRD Recruitment 2021: 56 vacancies for LDC, HMTS, Driver, and others on offer

By hindustantimes.com | Written by Akhilesh Nagari, Hindustan Times, New Delhi
PUBLISHED ON JAN 26, 2021 06:49 PM IST
  • Interested and eligible candidates can apply for the positions through a prescribed format on or before February 28, 2021.
Close
Aligarh Muslim University (Image courtesy: amu.ac.in)
Aligarh Muslim University (Image courtesy: amu.ac.in)

AMU buries time capsule to mark 100 years of institution

PTI, Aligarh
PUBLISHED ON JAN 26, 2021 06:07 PM IST
AMU buries time capsule to mark 100 years of institution
Close
JEE Mains 2021.(PTI)
JEE Mains 2021.(PTI)

JEE Mains 2021 correction window to open tomorrow, check details

By hindustantimes.com | Edited by Akhilesh Nagari, Hindustan Times, New Delhi
PUBLISHED ON JAN 26, 2021 05:05 PM IST
  • After the correction window opens, candidates who have registered for the JEE Mains 2021 will be able to make corrections in their application forms online at jeemain.nta.nic.in on or before January 30, 2021.
Close
Student maintain social distancing in class after schools reopened more than 9 months after they were closed due to Covid-19.(HT PHOTO)
Student maintain social distancing in class after schools reopened more than 9 months after they were closed due to Covid-19.(HT PHOTO)

3 states to open schools from tomorrow, put strict Covid-19 norms in place

By hindustantimes.com | Written by Harshit Sabarwal, Hindustan Times, New Delhi
UPDATED ON JAN 26, 2021 03:22 PM IST
Schools and other educational institutions across the country had been shut for months after the Centre imposed a lockdown and other related restrictions in the initial phase of the pandemic.
Close
PM Modi.(Photo: BJP4India/ Twitter)
PM Modi.(Photo: BJP4India/ Twitter)

Bihar's "cycle girl" interacts with PM Modi

PTI, Darbhanga
UPDATED ON JAN 26, 2021 02:42 PM IST
The 16-year-old was among 32 children from across the country who reached their respective National Informatics Centre offices and interacted with the Prime Minister via video conferencing.
Close
GJUST clerk admit card 2021.(Screengrab )
GJUST clerk admit card 2021.(Screengrab )

GJUST clerk admit card 2021 released, here's direct link

By hindustantimes.com | Edited by Akhilesh Nagari, Hindustan Times, New Delhi
PUBLISHED ON JAN 26, 2021 01:00 PM IST
  • Candidates who have registered for the typing test can download their admit card online at gjust.ac.in.
Close
Representational image.
Representational image.

College dropout becomes billionaire with chinese gaming platform

Bloomberg
PUBLISHED ON JAN 26, 2021 12:00 PM IST
Shares in his indie game distributor XD Inc. rose 24% on the first trading day of 2021 after Huawei Technologies Co. temporarily removed all Tencent Holdings Ltd. games from its app store in a dispute over their revenue split.
Close
Punjab chief minister Amarinder Singh(Sanchit Khanna/HT photo)
Punjab chief minister Amarinder Singh(Sanchit Khanna/HT photo)

Punjab CM launches self-employment loan mela

PTI, Patiala
UPDATED ON JAN 26, 2021 11:18 AM IST
A token of 1,000 loan sanction certificates were handed over to beneficiaries as a symbolic gesture across the state, with the chief minister handing over certificates to five beneficiaries.
Close
Pedestrians walk through Harvard Yard on the closed Harvard University campus in Cambridge, Massachusetts, US.(Bloomberg)
Pedestrians walk through Harvard Yard on the closed Harvard University campus in Cambridge, Massachusetts, US.(Bloomberg)

Harvard applications surge as students flock to top names

Bloomberg
PUBLISHED ON JAN 26, 2021 10:07 AM IST
Applications to Harvard University’s undergraduate college for regular decision surged more than 42% for the 2021-22 academic year.
Close
SSC JHT final answer key 2020.(HT file)
SSC JHT final answer key 2020.(HT file)

SSC JHT final answer key 2020 released, here's direct link

By hindustantimes.com | Edited by Akhilesh Nagari, Hindustan Times, New Delhi
PUBLISHED ON JAN 26, 2021 09:32 AM IST
  • Candidates who have appeared in the recruitment examination can take a print out of the final answer key online at ssc.nic.in on or before February 24, 2021.
Close
IBPS PO mains admit card 2020.(Screengrab )
IBPS PO mains admit card 2020.(Screengrab )

IBPS PO mains admit card 2020 released, here's direct link

By hindustantimes.com | Edited by Akhilesh Nagari, Hindustan Times, New Delhi
PUBLISHED ON JAN 26, 2021 09:05 AM IST
  • Candidates who have qualified in the IBPS PO Prelims Exam can download their admit card for IBPS PO mains online at ibps.in on or before February 4, 2021.
Close
AP EAMCET 2nd phase allotment result 2020.(PTI file)
AP EAMCET 2nd phase allotment result 2020.(PTI file)

AP EAMCET second phase allotment result 2020 declared, here's direct link

By hindustantimes.com | Edited by Akhilesh Nagari
PUBLISHED ON JAN 26, 2021 08:36 AM IST
  • Candidates who have applied for admission can check the AP EAMCET second phase allotment result 2020 online at apeamcet.nic.in.
Close
Odisha Chief Minister Naveen Patnaik.(HT file)
Odisha Chief Minister Naveen Patnaik.(HT file)

Odisha CM requests judges, leaders to join Mo School campaign

ANI, Bhubaneswar
PUBLISHED ON JAN 26, 2021 08:27 AM IST
  • Patnaik had launched the "Mo School" campaign in November 2017 in response to philanthropic interest from alumni of schools of Odisha, residing in India and abroad.
Close
Delhi Deputy Chief Minister Manish Sisodia on Wednesday said that the government is brainstorming on how early schools can be reopened in the national capital.(Arvind Yadav/HT file)
Delhi Deputy Chief Minister Manish Sisodia on Wednesday said that the government is brainstorming on how early schools can be reopened in the national capital.(Arvind Yadav/HT file)

US Embassy, Delhi govt launch English teaching programme for teachers

PTI
PUBLISHED ON JAN 25, 2021 11:23 PM IST
It is a 10-week-long online English teaching programme for 700 pre-service teachers from all women colleges of Delhi.
Close
With the objective of instilling among students the importance of having a definite ‘Purpose’ in life for shaping their career, FLAME University hosted FLAME University Purpose Summit 2021 on January 23-24.(Business Wire India)
With the objective of instilling among students the importance of having a definite ‘Purpose’ in life for shaping their career, FLAME University hosted FLAME University Purpose Summit 2021 on January 23-24.(Business Wire India)

Liberal education is going to be the future of education: FLAME University VC

By Nilesh Mathur
PUBLISHED ON JAN 25, 2021 08:46 PM IST
  • Universities need to explore the uncharted path and innovative methods when it comes to pedagogy, and playing the role of facilitators in a student's journey of finding their goals and preparing them for their future.
Close
SHARE
Story Saved
OPEN APP