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Harvard liver specialist shares 4 skin changes that indicate you have liver disease: ‘Itching without a clear cause’

Updated on: Jul 28, 2025, 09:14:34 IST
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Liver specialist shares 4 skin changes that could indicate underlying liver disease. (Adobe Stock)
Liver specialist shares 4 skin changes that could indicate underlying liver disease. (Adobe Stock)

Changes in your skin might indicate that you have underlying liver disease. Liver specialist Dr Sethi highlights what these skin changes are. 

Your liver is a large and powerful organ that performs hundreds of essential functions in your body. One of its most important functions is filtering toxins from your blood. Liver disease refers to a condition that damages your liver over time. Therefore, timely detection and treatment are important.

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In an Instagram post shared on July 27, Dr Saurabh Sethi, MD, MPH, board-certified gastroenterologist, hepatologist, and interventional endoscopist trained at AIIMS, Harvard and Stanford, listed 4 skin changes to look out for that could point out that you have liver disease.

4 skin changes that indicate you have liver disease

Sharing the 4 skin changes that could indicate underlying liver disease, the liver specialist pointed out that you can easily check these symptoms at home. Let's find out what they are:

1. Jaundice

Yellowing of the skin and eyes due to elevated bilirubin levels. This is a classic sign of liver disease, as the liver is responsible for processing bilirubin.

2. Spider angiomas

Small dilated blood vessels that resemble spider webs, typically on the face, neck, or chest. These are caused by increased estrogen levels, which can occur in liver disease.

3. Palmer erythema

Redness and inflammation of the palms, often accompanied by swelling. This is due to increased blood flow and estrogen levels, which can be a sign of liver dysfunction.

4. Itching without a clear cause

Often worse at night. This can be due to bile salts building up in the skin, which can occur in liver problems.

Stages of chronic liver disease

According to the Cleveland Clinic, chronic liver disease progresses in roughly four stages: hepatitis, fibrosis, cirrhosis, and liver failure. Approximately 1.8 percent of US adults (4.5 million adults) have liver disease. Globally, it causes about 2 million deaths per year, or 4 percent of all deaths. Liver disease affects males twice as often as females.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

  • Krishna Pallavi Priya
    ABOUT THE AUTHOR
    Krishna Pallavi Priya

    Krishna Priya Pallavi is a journalist with over 9 years of experience, covering health, fashion, pop culture, travel, wellness, entertainment, festivals, mental health, art, decor, fitness, and sex and relationships. She is an alumna of the Indian Institute of Mass Communication (IIMC), Dhenkanal, and holds an undergraduate degree in Journalism and Mass Communication from Guru Gobind Singh Indraprastha University, Delhi. Her strong academic foundation informs her analytical and detail-oriented approach to storytelling, helping her uncover stories where none seem to exist. Before joining Hindustan Times, Pallavi worked with some of India’s leading media organisations. She spent close to three years at India Today, where she honed her newsroom skills and developed a sharp editorial sensibility. She also worked for over a year and a half at Vagabomb, ScoopWhoop’s feminist digital platform, where she explored stories through a gender-sensitive, socially aware lens. Pallavi has a deep interest in global fashion trends and international fashion seasons, and enjoys interviewing celebrities and tracking pop culture movements—interests that frequently translate into engaging, reader-friendly stories. Alongside lifestyle and entertainment, she has a keen eye for impactful health and wellness journalism, regularly interacting with doctors, designers, and digital content creators to bring nuance and credibility to her work. Born and raised in Haryana, Pallavi remains deeply connected to her ancestral roots in Odisha. Her ability to spot fresh angles brings curiosity and depth to stories she pursues. When not chasing deadlines, she enjoys spending time with her dog, planning her next vacation, reading, running new trails, and discovering new destinations.Read More

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