Excessive fat in diet

Published on Oct 29, 2004 05:41 PM IST

Excess of dietary fat accelerates breast cancer risk as it alters the activity of a group of genes in the body.

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PTI | ByAsian News International, Washington

Recent experiments conducted on rats at the University of Birmingham in Alabama, have revealed that excess of dietary fat accelerates breast cancer risk as it alters the activity of a group of genes.

The research team at the Departament de Biologia Cel7lular, de Fisiologia i d'Immunologia of the UAB has found that certain fats in the diet, commonly known as omega-6, accelerates breast cancer, increasing the malignancy of the disease.

They have identified four genes, one that has a completely unknown function, whose expression may be involved in enhancing breast cancer risk and consequently the researchers have emphasized on the importance of a moderate consumption of fats.

The team headed by Eduard Escrich, lecturer in the Departament de Biologia Cel7lular, de Fisiologia i d'Immunologia at the UAB also found that diets rich in the polyunsaturated fatty acids n-6, reduce the expression of a group of four genes, three of which are related to cellular differentiation and the fourth of which is a sequence with a totally unknown function, thereby accelerating the proliferation of tumours.

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