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Maryland doctor explains the dangers of alcohol withdrawal: ‘A brain chemistry problem, not just a lack of willpower’

Long-term consumption of alcohol makes the brain adapt to its constant presence. Quitting out of the blue disrupts the balance, says Dr Sood. 

Updated on: Feb 10, 2026 3:08 PM IST
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Drinking alcohol is one of the most common addictions and a known health-risk behaviour. And as with any such behaviour, it is notoriously difficult to quit.

Quitting alcohol without medical support has the risk of becoming life-threatening, shares Dr Sood. (Unsplash)
Quitting alcohol without medical support has the risk of becoming life-threatening, shares Dr Sood. (Unsplash)

People experience strong withdrawal symptoms while trying to stop drinking alcohol after an extended period of dependency. That includes physical pain and discomfort that many consider to be life-threatening.

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While there are institutions that help individuals through the journey, many among the general masses feel that it is simply a willpower problem that comes in the way of an individual quitting more than anything else. However, taking to Instagram on February 10, Dr Kunal Sood, a Maryland-based physician in anesthesiology and interventional pain medicine, elaborated that this is not the case.

Why quitting alcohol is difficult

“People say quitting alcohol cold turkey can kill you the same day,” observed Dr Sood. “And while that’s rare, severe alcohol withdrawal can be life-threatening if it is not managed properly.”

Alcohol acts as a “chemical brake” in the brain, he explained. It boosts calming signals in the organ via GABA (gamma-aminobutyric acid) and suppresses excitatory signals, such as glutamate.

In the case of an individual who has been drinking heavily for a long time, the brain adapts to the presence of alcohol all the time. It compensates for the alcohol by turning down its own calming system and increasing the level of excitation.

“When alcohol is suddenly removed, that balance collapses,” noted Dr Sood. “That calming effect is gone, but the overactive excitatory system remains. That’s when alcohol withdrawal begins.”

Alcohol withdrawal symptoms

According to Dr Sood, symptoms of alcohol withdrawal can start within hours of quitting, though they usually appear one to three days after the last drink.

Symptoms may include:

  • Tremors
  • Sweating
  • Anxiety
  • Nausea
  • Rapid heart rate
  • High blood pressure

In more severe cases, withdrawal can lead to seizures and delirium tremens, a dangerous state marked by confusion, hallucinations, and autonomic instability.

So while most people don’t die the same day they stop drinking, abrupt withdrawal in heavy or dependent drinkers can absolutely become life-threatening without treatment,” observed Dr Sood.

That is why medical supervision is important when it comes to quitting long-term alcohol dependency. It allows doctors to use medications, fluids, and monitoring to keep the nervous system stable and prevent complications.

“Stopping alcohol is a positive step, but how you stop matters,” noted Dr Sood, adding that “alcohol withdrawal is a brain chemistry problem, not just a lack of willpower.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

  • Debapriya Bhattacharya
    ABOUT THE AUTHOR
    Debapriya Bhattacharya

    Debapriya Bhattacharya is a Content Producer at Hindustan Times. He started his career in 2022, working in newsrooms in beats like education, US news, trending stories, and entertainment. In his new role in the lifestyle desk, he seeks to deliver a balanced blend of research-driven reporting and creative storytelling from health and recipes to art and culture. Science, philosophy, food and pop culture are what pump his veins and help bring heart to his stories. Debapriya tries to see out subjects that will allow him and readers to explore new frontiers and improve the quality of life for all. The explorations can be both external and internal, as thoughts seek to be as chaotic as the greater universe. As a citizen of the world, Debapriya has been fascinated by the lives of people across the globe throughout time. His curiosity leads him to explore new linguistic and cultural landscapes to broaden his horizons and deepen his understanding of global narratives. Beyond the newsroom, Debapriya loves to participate in debate and theatre, spaces that he considers to be holy grounds for nuance and self-expression. A graduate from Ashutosh College, University of Calcutta, Debapriya completed his Master's degree from the same university in 2022. An ambiverted bibliophile, he loves his solitude as much as he adores stimulating conversations. And despite his reverence for tech, libraries continue to be his favourite place for research.Read More

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