MHRA has identified 30 cases of rare blood clot events out of 18.1 million AstraZeneca doses administered up to March 24.(REUTERS)
MHRA has identified 30 cases of rare blood clot events out of 18.1 million AstraZeneca doses administered up to March 24.(REUTERS)

UK regulator says AstraZeneca Covid-19 vaccine safe after 7 blood clot deaths

  • Concerns over the AstraZeneca vaccine has already prompted some countries including Canada, France, Germany and the Netherlands to restrict its use to older people.
AP | , London
UPDATED ON APR 03, 2021 06:33 PM IST

Britain’s medicines regulator is urging people to continue taking the AstraZeneca coronavirus vaccine, despite revealing that seven people in the U.K. have died from rare blood clots after getting the jab.

The Medicines and Healthcare Regulatory Agency, or MHRA, said it wasn't clear if the shots are causing the clots, and that its “rigorous review into the U.K. reports of rare and specific types of blood clots is ongoing.”

Though the agency said late Friday that seven people had died as a result of developing blood clots, it didn’t disclose any information about their ages or health conditions.

In total, MHRA said had identified 30 cases of rare blood clot events out of 18.1 million AstraZeneca doses administered up to and including March 24. The risk associated with this type of blood clot is “very small,” it added.

“The benefits of Covid-19 vaccine AstraZeneca in preventing Covid-19 infection and its complications continue to outweigh any risks and the public should continue to get their vaccine when invited to do so,” said Dr. June Raine, the agency’s chief executive.

Concerns over the AstraZeneca vaccine has already prompted some countries including Canada, France, Germany and the Netherlands to restrict its use to older people. The U.K., which has rolled out coronavirus vaccines faster than other European nations, is particularly reliant on the AstraZeneca vaccine, which was developed by scientists at the University of Oxford.

Read | AstraZeneca Covid shot: Are women recipients more impacted by blood clot events?

MHRA's view about the relative benefits of the vaccine is shared by the European Medicines Agency. It has said a causal link between unusual blood clots in people who have had the vaccine is “not proven, but is possible," and that the benefits of the vaccine outweigh the risks of side effects. The World Health Organization has also urged countries to continue using the jab.

Adam Finn, a professor of pediatrics at the University of Bristol, said the “extreme rarity” of the blood-clotting events in the context of the millions of jabs administered in the U.K. makes the decision facing people very straightforward.

“Receiving the vaccine is by far the safest choice in terms of minimizing individual risk of serious illness or death,” he said.

A more detailed look at the MHRA’s findings show that of the 30 cases, 22 related to cerebral venous sinus thrombosis, which stops blood draining from the brain properly, and eight were connected with other thrombosis events with low platelets.

It said there were no reports of any blood-clotting events around the Pfizer/BioNTech vaccine, which has also been widely rolled out in the U.K.


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Indonesia had previously delayed administering the AstraZeneca vaccine following the blood clot reports, saying it was awaiting the results of a review by WHO.(Reuters)
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PUBLISHED ON APR 03, 2021 03:30 PM IST
  • Concerns over the AstraZeneca vaccine prompted some countries including Canada, France, Germany and the Netherlands to restrict its use to older people.
The rising number of blood-clot cases and the moves to suspend or limit shots have added to the uncertainty around the AstraZeneca vaccine. (Darryl Dyck/The Canadian Press via AP)(AP)
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Australia working with EU, UK to investigate AstraZeneca linked blood clot case

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PUBLISHED ON APR 03, 2021 02:41 PM IST
  • The Australian case, first reported on April 2, is currently being investigated by the country’s Therapeutic Goods Administration.
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