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Gastroenterologist warns liver cirrhosis can affect your brain, leading to symptoms like personality changes, tremors

Updated on: Aug 18, 2025, 11:33:19 IST
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When the liver sustains damage and loses its ability to remove toxins from the bloodstream effectively, it can lead to impaired brain function. (Adobe Stock)
When the liver sustains damage and loses its ability to remove toxins from the bloodstream effectively, it can lead to impaired brain function. (Adobe Stock)

Gastroenterologist Dr Salhab warns that liver cirrhosis can lead to overt hepatic encephalopathy, impacting brain function and overall well-being. 

Many don’t realise that cirrhosis, a severe form of chronic liver disease, can progress to a condition that can impact brain function. In an August 15 Instagram post, gastroenterologist Dr Joseph Salhab highlighted how problems with your liver health could affect your brain function.

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The gastroenterologist and liver specialist explained how overt hepatic encephalopathy (OHE), a condition which can eventually impact your brain due to the progression of a liver disease. Here's how it impacts your brain function:

How can overt hepatic encephalopathy (OHE) impact your brain?

In the post, Dr Salhab highlighted that liver disease can progress and eventually impact brain function. Explaining what OHE is, the gastroenterologist stressed that it is a complication of cirrhosis and occurs when the liver sustains damage and loses its ability to remove toxins from the bloodstream effectively, causing toxins to accumulate and lead to impaired brain function.

He explained, “This leads to a range of mental and physical symptoms that can significantly impact a person's well-being.” Symptoms associated with an episode of OHE can include:

  • confusion
  • disorientation
  • severe personality changes
  • changes in sleep patterns
  • tremors, and more.

On the surface, these symptoms may not seem connected to a decline in liver function, but the gastroenterologist pointed out that this is why it is always recommended to speak to your doctor about all of your symptoms.

However, Dr Salhab pointed out that despite the condition's complexities, it's important to note that the risk of other OHE episodes can be managed. “Understanding your condition is one of the most empowering steps you can take. I've heard from many patients and caregivers who said that they wish they knew what to look for, but they simply didn't have access to the right information. If you or someone you love is living with OHE, don't wait to learn more.”

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

  • Krishna Pallavi Priya
    ABOUT THE AUTHOR
    Krishna Pallavi Priya

    Krishna Priya Pallavi is a journalist with over 9 years of experience, covering health, fashion, pop culture, travel, wellness, entertainment, festivals, mental health, art, decor, fitness, and sex and relationships. She is an alumna of the Indian Institute of Mass Communication (IIMC), Dhenkanal, and holds an undergraduate degree in Journalism and Mass Communication from Guru Gobind Singh Indraprastha University, Delhi. Her strong academic foundation informs her analytical and detail-oriented approach to storytelling, helping her uncover stories where none seem to exist. Before joining Hindustan Times, Pallavi worked with some of India’s leading media organisations. She spent close to three years at India Today, where she honed her newsroom skills and developed a sharp editorial sensibility. She also worked for over a year and a half at Vagabomb, ScoopWhoop’s feminist digital platform, where she explored stories through a gender-sensitive, socially aware lens. Pallavi has a deep interest in global fashion trends and international fashion seasons, and enjoys interviewing celebrities and tracking pop culture movements—interests that frequently translate into engaging, reader-friendly stories. Alongside lifestyle and entertainment, she has a keen eye for impactful health and wellness journalism, regularly interacting with doctors, designers, and digital content creators to bring nuance and credibility to her work. Born and raised in Haryana, Pallavi remains deeply connected to her ancestral roots in Odisha. Her ability to spot fresh angles brings curiosity and depth to stories she pursues. When not chasing deadlines, she enjoys spending time with her dog, planning her next vacation, reading, running new trails, and discovering new destinations.Read More

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