Cardiovascular surgeon shares 3 advanced lab tests for a complete heart profile, that standard lipid panels don't cover
Standard lipid panels don't always cover underlying markers that might be affecting your cardiovascular health. Dr Jeremy London shares 3 advanced lab tests.
Most people rely on a standard lipid panel to gauge their heart health, but experts say those numbers don’t always tell the full story. While cholesterol levels provide a baseline, they don’t capture other critical factors like particle count, genetic markers, or inflammation - all of which can quietly raise your chances of developing heart disease. To get a more accurate picture of your cardiovascular health, certain advanced lab tests can help fill the gaps left by traditional panels.

Dr Jeremy London, a board-certified cardiothoracic surgeon with over 25 years of clinical experience, has revealed three tests that can provide a clearer picture of your heart and cardiovascular health, which the standard lipid profile does not cover. In an Instagram video posted on October 7, the cardiologist highlights key lab tests that can help assess your overall cardiovascular risk - and breaks down what each test actually measures and why it matters.
Apolipoprotein B (ApoB)
According to Dr London, ApoB measures the number of particles capable of carrying cholesterol into your bloodstream. While a lipid panel shows how much cholesterol you have, ApoB reveals how many particles are capable of delivering that cholesterol into the walls of your arteries. He explains, “It's not just how much cholesterol you have, it's how many dangerous bullets are circulating in the bloodstream. Elevated ApoB means more particles capable of penetrating and inflaming the arterial lining. That's what drives plaque formation.”
Lipoprotein(a) [Lp(a)]
The second test, Lipoprotein(a) - often written as Lp(a) or LP little a - measures a sticky, inflammatory particle that is largely determined by genetics. The cardiovascular surgeon highlights, “It's a sticky, highly inflammatory particle that not only accelerates plaque buildup, but also promotes clot formation. Standard cholesterol tests don't measure it, yet one in five people have elevated levels, and they don't even know it.”
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High-Sensitivity C-Reactive Protein (hs-CRP)
This test indicates inflammation in your body, which is a key driver of heart disease and often overlooked. Dr London explains, “Even if your cholesterol numbers look great, elevated CRP tells you that your arteries may be under attack from chronic inflammation, caused by things like poor sleep, stress, or metabolic dysfunction.”
A comprehensive profile of your heart
Together, these three tests - ApoB, Lp(a), and hs-CRP - offer a more comprehensive view of your long-term cardiovascular risk when combined with your regular lipid panel. The cardiologist emphasises, “Remember, that which is not measured cannot be improved upon,” and stresses that knowing these numbers can help you take proactive steps for your heart health.
Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. It is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.
ABOUT THE AUTHOREshana SahaEshana Saha is a fresh face in lifestyle and cultural journalism, bringing a refined, multidisciplinary perspective to the intersection of entertainment, fashion and holistic wellbeing. With less than a year of professional experience, she has quickly adapted to high-pressure editorial environments and currently works full-time with HT Media. Prior to this, she interned for nearly six months with Hindustan Times’ entertainment and lifestyle vertical, where she gained hands-on experience in digital reporting, trend analysis and editorial storytelling. Based in New Delhi, Eshana specialises in comprehensive coverage of major cultural moments — from international film press tours to the curated aesthetics of global fashion showcases, award shows and music-centred events. She holds a Bachelor’s degree in English from St Xavier’s University, Kolkata, and a Master’s degree in English from the University of Delhi, equipping her with a strong academic foundation and a keen ability to deconstruct complex cultural trends into clear, high-impact narratives. Beyond the red carpet, Eshana has developed a growing focus on health and wellbeing reporting. She bridges the gap between celebrity-driven trends and practical, evidence-informed lifestyle advice, ensuring her work remains both aspirational and grounded in editorial rigour. She has extensively covered the health implications of Delhi’s air pollution crisis, while also playing a key role in amplifying expert-led insights on women’s health and mental wellbeing, helping translate complex medical perspectives into informed, impactful public awareness. An artist at heart, she explores multiple creative forms — from visual arts and music to culinary experiments — and brings a creative’s eye for nuance, texture and detail to every story. Whether analysing runway dynamics or examining emerging wellness movements, she remains committed to accuracy and the highest standards of contemporary journalistic ethics.Read More
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