Colts vs. 49ers Monday Night Football final injury report: Are R. Pearsall, A. Richardson, and S. Gardner playing?

Ricky Pearsall, Anthony Richardson and Sauce Gardner have been ruled out for the Monday Night Football game of Colts vs. 49ers

Published on: Dec 23, 2025, 04:08:29 IST

By Shirin Gupta

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This week, the Indianapolis Colts (8-6) will host Monday Night Football for the first time since 2022 when they take on the San Francisco 49ers (10-4) at Lucas Oil Stadium.

In Frame: Indianapolis Colts quarterback Anthony Richardson Sr.: Ruled out for Colts vs 49ers Monday Night Football (AP Photo/Zach Bolinger, File) (AP)

While some prominent players will be absent from the primetime match, others are still questionable. Injuries to important offensive and defensive players might affect how the game plays out with playoff implications on the line.

Who is ruled out in 49ers?

The San Francisco 49ers will be without wide receiver Ricky Pearsall, who has been officially ruled out due to a knee and ankle injury suffered in last week’s game against the Tennessee Titans.

Pearsall did not practice all week and failed to clear the final hurdle for Monday night’s game.

Head coach Kyle Shanahan said after the team's final practice, “He was close, but not close enough.”

The 49ers will now be forced to adjust their receiving rotation without one of their emerging threats.

Along with Pearsall, cornerback Renardo Green will also be sidelined because of a lingering injury. QB Kurtis Rourke, who remains on injured reserve with a knee issue, will also not play. Defensive lineman Yetur Gross-Matos remains questionable with a hamstring injury.

The Colts will play without Gradner and Richardson

The Colts will be missing two key contributors on defence and offence, cornerback Sauce Gardner and quarterback Anthony Richardson.

Gardner remains OUT due to a persisting calf injury that has kept him off the field for multiple games.

Richardson, on the other hand, had practised with the team but was again ruled out due to lingering issues with his eye injury.

Additionally, wide receiver Anthony Gould (foot), Safety Daniel Scott (knee), and left tackle Bernhard Raimann (elbow) will remain out because of injury (mentioned in brackets).

The return of defensive end DeForest Buckner from injured reserve is a major plus for Indianapolis. He strengthens the front seven against a strong 49ers attack and could help offset some of the secondary loss.

ABOUT THE AUTHOR
Shirin Gupta
Shirin Gupta is a content producer with the Hindustan Times. She covers everything between politics, entertainment and sports at the US desk. Shirin got interested in political journalism during her time as a web editor at her college newspaper NCC News in Syracuse when she first started seeing the effects of national politics in life of her fellow colleagues. Shirin has worked on a wide range of fast-moving and developing stories locally when she was at NCC editing accessible reports for the audience. Her current role requires her to track real-time updates, verify information and present balanced coverage across diverse beats. Covering US politics from an international newsroom perspective has further deepened her understanding of how domestic decisions can have far-reaching global consequences. With a keen interest in international affairs, Shirin continues to build her expertise in geopolitics, policy shifts, and cross-border developments. She aims to learn and evolve her reporting in matters of geopolitics and international issues. Outside the newsroom Shirin writes about books and music for her personal blog. She is an avid consumer of pop culture and reveres literature.Read More

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