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AIIMS-trained gastroenterologist says eating and sleeping late at night affects liver function; 9 things to know

Did you know the liver can regenerate damaged cells and works according to its own clock? Discover more facts, including how daily habits affect its health.

Published on: Oct 19, 2025, 12:52:48 IST
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Your liver works quietly around the clock, processing everything you eat and drink throughout the day. While it has an incredible ability to regenerate, everyday habits - from poor sleep and late-night meals to exposure to toxins - can add strain over time. Taking care of this vital organ is essential for long-term health, and understanding how it functions can help you make smarter choices.

Dr Saurabh Sethi shares 9 essential things to know about your liver. (Pixabay)
Dr Saurabh Sethi shares 9 essential things to know about your liver. (Pixabay)

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Dr Saurabh Sethi, a gastroenterologist trained at AIIMS, Harvard and Stanford Universities, is breaking down nine essential facts you need to know about your liver.

In an Instagram post shared on October 19, the gastroenterologist explains that while the liver has the incredible power to regenerate, habits like poor sleep, late-night eating, and exposure to toxins can compromise its efficiency over time.

Your liver can regenerate

According to Dr Sethi, the liver can regenerate damaged cells, but that does not make it invincible. He explains, “It’s not invincible, and it can regrow damaged cells, but chronic injury leads to scarring that can’t be reversed.”

Coffee is liver medicine

Dr Sethi states that coffee isn’t just a morning pick-me-up or a fix for the afternoon slump - it can actually act as medicine for the liver. He states, “Three plus cups daily (is) linked to 40 percent lower risk of cirrhosis and liver cancer. Just skip the sugar and cream.” He also cautions that individual caffeine sensitivity varies, and excessive coffee intake may cause insomnia, palpitations, or anxiety.

Fatty liver

The gastroenterologist highlights that cases of fatty liver are more common than you think, even among non-drinkers. He states, “Fatty liver affects one in three adults, even non-drinkers. Nonalcoholic fatty liver disease (NAFLD) is skyrocketing and often remains silent until serious damage.”

Liver processes everything

Dr Sethi warns that everything you swallow is processed by the liver, including your medications. He stresses, “Over-the-counter painkillers like acetaminophen in high doses can cause deadly liver damage. Always confirm the correct dosage with your doctor.”

Liver and sleep

Your sleep quality is directly linked to liver repair. The gastroenterologist explains that poor sleep can disrupt liver metabolism, hampering the organ’s ability to clear toxins effectively. He recommends getting seven to nine hours of sleep every day, without compromise.

The liver clock

According to Dr Sethi, your liver has its own clock, and hence the circadian rhythm matters. He highlights, “Eating late at night stresses your liver’s natural detox cycle, increasing fat accumulation.”

Knowing how your liver functions is key to protecting its health. (Image generated via Google Gemini)
Knowing how your liver functions is key to protecting its health. (Image generated via Google Gemini)

Hidden liver killers

Common household chemicals, including cleaning products, pesticides, and even some cosmetics contain toxins that the liver must filter, adding extra strain to the organ. The gastroenterologist recommends opting for natural alternatives instead.

Supplements

The gastroenterologist warns that supplements are not always safe for the liver. He explains, “Some herbal supplements and high-dose vitamins can cause liver inflammation or damage. Always check with your doctor.”

The role of hydration

Dr Sethi stresses that hydration supports liver detoxification. He recommends drinking at least two to three litres of water every day because drinking enough water helps the liver flush out toxins efficiently.

Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. It is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

  • Eshana Saha
    ABOUT THE AUTHOR
    Eshana Saha

    Eshana Saha is a fresh face in lifestyle and cultural journalism, bringing a refined, multidisciplinary perspective to the intersection of entertainment, fashion and holistic wellbeing. With less than a year of professional experience, she has quickly adapted to high-pressure editorial environments and currently works full-time with HT Media. Prior to this, she interned for nearly six months with Hindustan Times’ entertainment and lifestyle vertical, where she gained hands-on experience in digital reporting, trend analysis and editorial storytelling. Based in New Delhi, Eshana specialises in comprehensive coverage of major cultural moments — from international film press tours to the curated aesthetics of global fashion showcases, award shows and music-centred events. She holds a Bachelor’s degree in English from St Xavier’s University, Kolkata, and a Master’s degree in English from the University of Delhi, equipping her with a strong academic foundation and a keen ability to deconstruct complex cultural trends into clear, high-impact narratives. Beyond the red carpet, Eshana has developed a growing focus on health and wellbeing reporting. She bridges the gap between celebrity-driven trends and practical, evidence-informed lifestyle advice, ensuring her work remains both aspirational and grounded in editorial rigour. She has extensively covered the health implications of Delhi’s air pollution crisis, while also playing a key role in amplifying expert-led insights on women’s health and mental wellbeing, helping translate complex medical perspectives into informed, impactful public awareness. An artist at heart, she explores multiple creative forms — from visual arts and music to culinary experiments — and brings a creative’s eye for nuance, texture and detail to every story. Whether analysing runway dynamics or examining emerging wellness movements, she remains committed to accuracy and the highest standards of contemporary journalistic ethics.Read More

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